A collaborative partner across the development journey
We support biologics programmes from a sequence through to GMP material. Engage us for a single developability assessment, a stable pool, or an integrated programme that carries your molecule from discovery to a documented clonal cell line and a scalable, transferable process.
From sequence to GMP supply
| Service | What you get | Typical input | Stage |
|---|---|---|---|
| Developability & sequence assessmentIs this molecule expressible? | Sequence liabilities, expressibility & manufacturability risk map | Gene / amino-acid sequence | |
| Cell line development & clone selection | High-expressing clonal line, monoclonality & stability data | Confirmed construct | |
| Upstream & downstream process development | Optimised fed-batch, purification train, scale-up & product quality | Selected production clone | |
| Analytical & GMP material supply | Analytical package, master cell bank & GMP-representative material | Locked process |
Engagements can start at any stage. The marked stage shows where each service sits on the path from sequence to GMP supply; programmes are scoped to protect timeline and product quality.
From sequence to manufacturable cell line + process
Our integrated expression programme brings assessment, cell line development, process and analytical work under one team and one timeline. We start by checking the sequence for expressibility and liabilities, generate and select a high-expressing clone, and lock an upstream and downstream process.
The output is a documented, regulatory-ready production cell line with a scalable process and a coherent CMC narrative — the package a programme needs to progress with confidence toward cGMP and first-in-human studies.
Flexible by design
Feasibility & pool express
A fixed-scope study to answer one question: will this molecule express well, and how fast can we get representative material from a stable pool? Fast, candid and material-sparing.
Full cell-line + process programme
End-to-end development with defined stage-gates, from construct to a documented clonal line, an optimised scalable process and a GMP-ready analytical package.
Tech transfer & deployment
Transfer of the cell line and process into your facility or a CDMO of your choice, with documentation, training and hands-on support to reproduce performance.
Scope a programme with us
Tell us where your molecule is today and we'll propose the most efficient route to a manufacturable cell line and a confident clinical decision.